Physical Properties | | | |
Molecular Weight: 351.49 g/mol | logS: -4.45528 | SlogP: 5.1902 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0885684 | Sterimol/B1: 2.03649 | Sterimol/B2: 3.43157 | Sterimol/B3: 4.3969 |
Sterimol/B4: 10.8389 | Sterimol/L: 16.7922 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.215 | Positive charged surface: 448.226 | Negative charged surface: 200.989 | Volume: 372.125 |
Hydrophobic surface: 553.487 | Hydrophilic surface: 95.728 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |