Physical Properties | | | |
Molecular Weight: 374.844 g/mol | logS: -5.7605 | SlogP: 4.8165 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0587011 | Sterimol/B1: 3.76545 | Sterimol/B2: 4.07044 | Sterimol/B3: 4.53195 |
Sterimol/B4: 5.77235 | Sterimol/L: 17.7527 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 586.048 | Positive charged surface: 264.01 | Negative charged surface: 322.038 | Volume: 325.125 |
Hydrophobic surface: 518.271 | Hydrophilic surface: 67.777 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |