Physical Properties | | | |
Molecular Weight: 404.518 g/mol | logS: -3.06188 | SlogP: 2.9849 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.173417 | Sterimol/B1: 2.74996 | Sterimol/B2: 4.38784 | Sterimol/B3: 6.52267 |
Sterimol/B4: 9.00157 | Sterimol/L: 16.0572 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.037 | Positive charged surface: 435.792 | Negative charged surface: 212.907 | Volume: 405.75 |
Hydrophobic surface: 571.948 | Hydrophilic surface: 110.089 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |