Physical Properties | | | |
Molecular Weight: 421.544 g/mol | logS: -3.74178 | SlogP: 2.4549 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.164964 | Sterimol/B1: 2.40168 | Sterimol/B2: 3.93334 | Sterimol/B3: 6.44885 |
Sterimol/B4: 10.953 | Sterimol/L: 15.01 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 686.096 | Positive charged surface: 440.956 | Negative charged surface: 212.16 | Volume: 424.375 |
Hydrophobic surface: 628.309 | Hydrophilic surface: 57.787 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |