Physical Properties | | | |
Molecular Weight: 411.586 g/mol | logS: -6.4164 | SlogP: 5.5129 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.43919 | Sterimol/B1: 2.03035 | Sterimol/B2: 3.94375 | Sterimol/B3: 7.9782 |
Sterimol/B4: 8.99245 | Sterimol/L: 14.634 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 689.921 | Positive charged surface: 520.718 | Negative charged surface: 169.203 | Volume: 432.875 |
Hydrophobic surface: 556.716 | Hydrophilic surface: 133.205 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |