Physical Properties | | | |
Molecular Weight: 407.311 g/mol | logS: -6.32072 | SlogP: 5.9089 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.153968 | Sterimol/B1: 1.969 | Sterimol/B2: 2.10827 | Sterimol/B3: 6.26296 |
Sterimol/B4: 9.75072 | Sterimol/L: 16.8353 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 646.206 | Positive charged surface: 346.11 | Negative charged surface: 300.096 | Volume: 362.375 |
Hydrophobic surface: 625.218 | Hydrophilic surface: 20.988 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |