Physical Properties | | | |
Molecular Weight: 417.514 g/mol | logS: -5.14759 | SlogP: 2.3488 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0531144 | Sterimol/B1: 2.51685 | Sterimol/B2: 3.51853 | Sterimol/B3: 3.79854 |
Sterimol/B4: 11.5501 | Sterimol/L: 16.9669 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.962 | Positive charged surface: 445.805 | Negative charged surface: 232.157 | Volume: 365 |
Hydrophobic surface: 519.053 | Hydrophilic surface: 158.909 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |