Physical Properties | | | |
Molecular Weight: 410.497 g/mol | logS: -3.57101 | SlogP: 3.5043 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.101022 | Sterimol/B1: 2.01006 | Sterimol/B2: 3.49227 | Sterimol/B3: 5.05036 |
Sterimol/B4: 12.1925 | Sterimol/L: 16.0913 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.591 | Positive charged surface: 428.59 | Negative charged surface: 213.267 | Volume: 395 |
Hydrophobic surface: 591.334 | Hydrophilic surface: 83.257 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |