Physical Properties | | | |
Molecular Weight: 380.423 g/mol | logS: -5.37318 | SlogP: 3.63042 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.191754 | Sterimol/B1: 2.13583 | Sterimol/B2: 4.06601 | Sterimol/B3: 5.09413 |
Sterimol/B4: 11.2685 | Sterimol/L: 15.7511 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 635.257 | Positive charged surface: 407.543 | Negative charged surface: 227.714 | Volume: 356.25 |
Hydrophobic surface: 541.812 | Hydrophilic surface: 93.445 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |