Physical Properties | | | |
Molecular Weight: 414.893 g/mol | logS: -5.02308 | SlogP: 4.31582 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0779878 | Sterimol/B1: 2.03446 | Sterimol/B2: 5.81879 | Sterimol/B3: 5.88788 |
Sterimol/B4: 10.3657 | Sterimol/L: 20.4405 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 763.973 | Positive charged surface: 457.66 | Negative charged surface: 306.313 | Volume: 387.875 |
Hydrophobic surface: 615.824 | Hydrophilic surface: 148.149 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |