Physical Properties | | | |
Molecular Weight: 415.88 g/mol | logS: -6.8909 | SlogP: 5.2309 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0394094 | Sterimol/B1: 2.53659 | Sterimol/B2: 3.30557 | Sterimol/B3: 3.94973 |
Sterimol/B4: 11.4404 | Sterimol/L: 18.7237 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 671.037 | Positive charged surface: 312.02 | Negative charged surface: 353.323 | Volume: 386.125 |
Hydrophobic surface: 577.249 | Hydrophilic surface: 93.788 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |