Physical Properties | | | |
Molecular Weight: 408.482 g/mol | logS: -5.46424 | SlogP: 3.2951 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0158343 | Sterimol/B1: 2.43428 | Sterimol/B2: 2.5671 | Sterimol/B3: 4.00653 |
Sterimol/B4: 9.86088 | Sterimol/L: 20.4466 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 699.65 | Positive charged surface: 418.217 | Negative charged surface: 281.432 | Volume: 378.5 |
Hydrophobic surface: 477.934 | Hydrophilic surface: 221.716 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |