Physical Properties | | | |
Molecular Weight: 321.373 g/mol | logS: -3.09282 | SlogP: 2.2343 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.241075 | Sterimol/B1: 2.63206 | Sterimol/B2: 2.66212 | Sterimol/B3: 6.01691 |
Sterimol/B4: 8.45621 | Sterimol/L: 12.6988 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 587.427 | Positive charged surface: 394.239 | Negative charged surface: 193.188 | Volume: 315.875 |
Hydrophobic surface: 444.908 | Hydrophilic surface: 142.519 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |