Physical Properties | | | |
Molecular Weight: 401.55 g/mol | logS: -5.59589 | SlogP: 6.0855 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.207379 | Sterimol/B1: 2.35528 | Sterimol/B2: 3.10591 | Sterimol/B3: 4.6919 |
Sterimol/B4: 10.818 | Sterimol/L: 14.5816 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.15 | Positive charged surface: 430.688 | Negative charged surface: 218.462 | Volume: 413.75 |
Hydrophobic surface: 600.776 | Hydrophilic surface: 48.374 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |