Physical Properties | | | |
Molecular Weight: 412.551 g/mol | logS: -3.77366 | SlogP: 2.7994 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.251204 | Sterimol/B1: 2.42221 | Sterimol/B2: 2.49635 | Sterimol/B3: 7.09568 |
Sterimol/B4: 10.8901 | Sterimol/L: 13.4564 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 663.474 | Positive charged surface: 494.939 | Negative charged surface: 168.535 | Volume: 396 |
Hydrophobic surface: 535.122 | Hydrophilic surface: 128.352 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |