Physical Properties | | | |
Molecular Weight: 370.166 g/mol | logS: -2.76624 | SlogP: 1.562 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0336969 | Sterimol/B1: 2.65321 | Sterimol/B2: 2.8458 | Sterimol/B3: 3.0832 |
Sterimol/B4: 6.04013 | Sterimol/L: 16.4355 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 498.3 | Positive charged surface: 229.821 | Negative charged surface: 268.479 | Volume: 264.375 |
Hydrophobic surface: 376.201 | Hydrophilic surface: 122.099 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |