Physical Properties | | | |
Molecular Weight: 421.453 g/mol | logS: -5.42015 | SlogP: 3.3395 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0131318 | Sterimol/B1: 2.36338 | Sterimol/B2: 2.86807 | Sterimol/B3: 3.6895 |
Sterimol/B4: 9.46741 | Sterimol/L: 20.9963 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 723.256 | Positive charged surface: 470.153 | Negative charged surface: 242.363 | Volume: 393.625 |
Hydrophobic surface: 589.274 | Hydrophilic surface: 133.982 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |