Physical Properties | | | |
Molecular Weight: 425.481 g/mol | logS: -4.84328 | SlogP: 3.57134 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.202835 | Sterimol/B1: 3.45479 | Sterimol/B2: 3.67832 | Sterimol/B3: 5.36943 |
Sterimol/B4: 7.90005 | Sterimol/L: 15.7794 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 653.375 | Positive charged surface: 460.491 | Negative charged surface: 192.884 | Volume: 405.125 |
Hydrophobic surface: 480.025 | Hydrophilic surface: 173.35 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |