Physical Properties | | | |
Molecular Weight: 409.486 g/mol | logS: -3.08171 | SlogP: 3.1058 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0726812 | Sterimol/B1: 3.17625 | Sterimol/B2: 5.12601 | Sterimol/B3: 5.25546 |
Sterimol/B4: 5.42697 | Sterimol/L: 20.3414 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 700.917 | Positive charged surface: 509.581 | Negative charged surface: 191.336 | Volume: 401 |
Hydrophobic surface: 544.259 | Hydrophilic surface: 156.658 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |