Physical Properties | | | |
Molecular Weight: 382.416 g/mol | logS: -3.02303 | SlogP: 2.1737 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.10018 | Sterimol/B1: 3.2101 | Sterimol/B2: 5.33383 | Sterimol/B3: 5.87438 |
Sterimol/B4: 8.00247 | Sterimol/L: 16.8765 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 654.453 | Positive charged surface: 445.422 | Negative charged surface: 209.031 | Volume: 363.625 |
Hydrophobic surface: 517.799 | Hydrophilic surface: 136.654 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |