Physical Properties | | | |
Molecular Weight: 305.334 g/mol | logS: -0.45958 | SlogP: -0.5834 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.111363 | Sterimol/B1: 2.31702 | Sterimol/B2: 4.83209 | Sterimol/B3: 5.10353 |
Sterimol/B4: 6.17919 | Sterimol/L: 14.877 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 536.464 | Positive charged surface: 365.25 | Negative charged surface: 171.214 | Volume: 287.25 |
Hydrophobic surface: 354.725 | Hydrophilic surface: 181.739 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |