Physical Properties | | | |
Molecular Weight: 306.342 g/mol | logS: -0.38393 | SlogP: -0.9828 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0902919 | Sterimol/B1: 3.36732 | Sterimol/B2: 3.84025 | Sterimol/B3: 3.97576 |
Sterimol/B4: 7.01699 | Sterimol/L: 15.5661 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 543.946 | Positive charged surface: 381.266 | Negative charged surface: 162.68 | Volume: 293 |
Hydrophobic surface: 347.08 | Hydrophilic surface: 196.866 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |