Physical Properties | | | |
Molecular Weight: 410.494 g/mol | logS: -5.35104 | SlogP: 2.97067 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0368612 | Sterimol/B1: 2.51055 | Sterimol/B2: 3.36935 | Sterimol/B3: 4.0734 |
Sterimol/B4: 9.18549 | Sterimol/L: 19.1214 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 691.69 | Positive charged surface: 398.795 | Negative charged surface: 281.414 | Volume: 377.625 |
Hydrophobic surface: 585.814 | Hydrophilic surface: 105.876 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |