Physical Properties | | | |
Molecular Weight: 386.428 g/mol | logS: -4.7627 | SlogP: 3.2854 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.117209 | Sterimol/B1: 2.04279 | Sterimol/B2: 3.06029 | Sterimol/B3: 5.8152 |
Sterimol/B4: 9.88026 | Sterimol/L: 16.8347 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 647.145 | Positive charged surface: 359.132 | Negative charged surface: 288.013 | Volume: 340.875 |
Hydrophobic surface: 508.321 | Hydrophilic surface: 138.824 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |