Physical Properties | | | |
Molecular Weight: 402.45 g/mol | logS: -6.36567 | SlogP: 4.25039 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.176659 | Sterimol/B1: 2.2967 | Sterimol/B2: 2.51143 | Sterimol/B3: 7.22891 |
Sterimol/B4: 9.66762 | Sterimol/L: 16.731 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 673.814 | Positive charged surface: 408.51 | Negative charged surface: 262.524 | Volume: 389 |
Hydrophobic surface: 569.15 | Hydrophilic surface: 104.664 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |