Physical Properties | | | |
Molecular Weight: 383.451 g/mol | logS: -4.89536 | SlogP: 4.07567 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.221267 | Sterimol/B1: 2.79178 | Sterimol/B2: 4.45414 | Sterimol/B3: 6.37093 |
Sterimol/B4: 7.75663 | Sterimol/L: 15.5892 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 609.391 | Positive charged surface: 323.442 | Negative charged surface: 285.95 | Volume: 373.375 |
Hydrophobic surface: 448.696 | Hydrophilic surface: 160.695 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |