Physical Properties | | | |
Molecular Weight: 402.427 g/mol | logS: -3.58757 | SlogP: 1.91327 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0921578 | Sterimol/B1: 2.62341 | Sterimol/B2: 3.54004 | Sterimol/B3: 4.03834 |
Sterimol/B4: 6.64303 | Sterimol/L: 16.9875 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 603.874 | Positive charged surface: 369.619 | Negative charged surface: 231.459 | Volume: 343.375 |
Hydrophobic surface: 415.402 | Hydrophilic surface: 188.472 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |