Physical Properties | | | |
Molecular Weight: 419.319 g/mol | logS: -4.4308 | SlogP: 3.6907 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.232877 | Sterimol/B1: 2.19362 | Sterimol/B2: 4.89223 | Sterimol/B3: 6.10956 |
Sterimol/B4: 9.43616 | Sterimol/L: 15.2308 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 653.773 | Positive charged surface: 427.314 | Negative charged surface: 226.459 | Volume: 368.875 |
Hydrophobic surface: 611.535 | Hydrophilic surface: 42.238 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |