Physical Properties | | | |
Molecular Weight: 395.289 g/mol | logS: -6.67252 | SlogP: 6.4267 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0820238 | Sterimol/B1: 2.55511 | Sterimol/B2: 2.66567 | Sterimol/B3: 4.32213 |
Sterimol/B4: 12.499 | Sterimol/L: 15.3279 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 623.387 | Positive charged surface: 278.209 | Negative charged surface: 345.178 | Volume: 354.75 |
Hydrophobic surface: 604.246 | Hydrophilic surface: 19.141 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |