Physical Properties | | | |
Molecular Weight: 423.533 g/mol | logS: -4.91482 | SlogP: 2.44552 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0880592 | Sterimol/B1: 3.72536 | Sterimol/B2: 4.34803 | Sterimol/B3: 6.09204 |
Sterimol/B4: 9.05666 | Sterimol/L: 18.5818 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 754.979 | Positive charged surface: 523.03 | Negative charged surface: 231.95 | Volume: 433.375 |
Hydrophobic surface: 595.279 | Hydrophilic surface: 159.7 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |