Physical Properties | | | |
Molecular Weight: 402.538 g/mol | logS: -6.99346 | SlogP: 5.36799 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.07615 | Sterimol/B1: 2.86872 | Sterimol/B2: 4.63799 | Sterimol/B3: 5.54434 |
Sterimol/B4: 7.34332 | Sterimol/L: 16.8371 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 679.08 | Positive charged surface: 446.742 | Negative charged surface: 232.338 | Volume: 407.875 |
Hydrophobic surface: 575.77 | Hydrophilic surface: 103.31 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |