Physical Properties | | | |
Molecular Weight: 404.882 g/mol | logS: -5.98774 | SlogP: 2.3644 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0122945 | Sterimol/B1: 2.66869 | Sterimol/B2: 3.4109 | Sterimol/B3: 3.42357 |
Sterimol/B4: 5.61204 | Sterimol/L: 22.4614 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 671.462 | Positive charged surface: 393.738 | Negative charged surface: 271.479 | Volume: 352.25 |
Hydrophobic surface: 440.221 | Hydrophilic surface: 231.241 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |