Physical Properties | | | |
Molecular Weight: 385.551 g/mol | logS: -6.3047 | SlogP: 5.89927 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.147254 | Sterimol/B1: 2.40878 | Sterimol/B2: 3.1048 | Sterimol/B3: 5.11589 |
Sterimol/B4: 9.84364 | Sterimol/L: 16.0086 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 646.769 | Positive charged surface: 383.639 | Negative charged surface: 263.131 | Volume: 403.625 |
Hydrophobic surface: 597.912 | Hydrophilic surface: 48.857 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |