Physical Properties | | | |
Molecular Weight: 412.494 g/mol | logS: -3.1988 | SlogP: 1.19617 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.128861 | Sterimol/B1: 2.54903 | Sterimol/B2: 2.79894 | Sterimol/B3: 5.25317 |
Sterimol/B4: 12.0384 | Sterimol/L: 16.1711 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 697.825 | Positive charged surface: 527.895 | Negative charged surface: 169.93 | Volume: 391.375 |
Hydrophobic surface: 510.714 | Hydrophilic surface: 187.111 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |