Physical Properties | | | |
Molecular Weight: 411.957 g/mol | logS: -8.22298 | SlogP: 5.3008 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0285515 | Sterimol/B1: 2.4885 | Sterimol/B2: 4.4308 | Sterimol/B3: 6.77701 |
Sterimol/B4: 8.19693 | Sterimol/L: 17.3498 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 679.698 | Positive charged surface: 373.258 | Negative charged surface: 295.08 | Volume: 384.625 |
Hydrophobic surface: 568.553 | Hydrophilic surface: 111.145 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |