Physical Properties | | | |
Molecular Weight: 381.476 g/mol | logS: -4.08442 | SlogP: 3.3962 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0211092 | Sterimol/B1: 2.25727 | Sterimol/B2: 3.27226 | Sterimol/B3: 4.36545 |
Sterimol/B4: 6.23072 | Sterimol/L: 24.1719 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 700.035 | Positive charged surface: 471.375 | Negative charged surface: 228.66 | Volume: 378.375 |
Hydrophobic surface: 579.437 | Hydrophilic surface: 120.598 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |