Physical Properties | | | |
Molecular Weight: 398.843 g/mol | logS: -3.6119 | SlogP: 2.7474 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.285679 | Sterimol/B1: 4.18408 | Sterimol/B2: 4.62455 | Sterimol/B3: 5.8097 |
Sterimol/B4: 7.12359 | Sterimol/L: 14.7496 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 619.945 | Positive charged surface: 408.534 | Negative charged surface: 211.41 | Volume: 357.5 |
Hydrophobic surface: 434.405 | Hydrophilic surface: 185.54 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |