Physical Properties | | | |
Molecular Weight: 200.154 g/mol | logS: 0.43289 | SlogP: -1.9388 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.10443 | Sterimol/B1: 2.24719 | Sterimol/B2: 3.95142 | Sterimol/B3: 3.97672 |
Sterimol/B4: 4.54577 | Sterimol/L: 10.9659 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 355.349 | Positive charged surface: 228.175 | Negative charged surface: 127.174 | Volume: 155.5 |
Hydrophobic surface: 57.9577 | Hydrophilic surface: 297.3913 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |