Physical Properties | | | |
Molecular Weight: 255.138 g/mol | logS: -0.31018 | SlogP: -0.1256 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0337124 | Sterimol/B1: 2.7646 | Sterimol/B2: 3.10577 | Sterimol/B3: 3.16339 |
Sterimol/B4: 6.00477 | Sterimol/L: 10.5026 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 404.399 | Positive charged surface: 215.487 | Negative charged surface: 188.912 | Volume: 185 |
Hydrophobic surface: 34.8179 | Hydrophilic surface: 369.5811 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 8 | Hydrogen bond acceptors: 9 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |