Physical Properties | | | |
Molecular Weight: 378.88 g/mol | logS: -4.46943 | SlogP: 3.0995 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.092082 | Sterimol/B1: 2.32151 | Sterimol/B2: 2.68106 | Sterimol/B3: 4.9727 |
Sterimol/B4: 11.1071 | Sterimol/L: 14.7645 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 617.967 | Positive charged surface: 313.839 | Negative charged surface: 304.128 | Volume: 344.5 |
Hydrophobic surface: 474.162 | Hydrophilic surface: 143.805 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |