Physical Properties | | | |
Molecular Weight: 401.405 g/mol | logS: -4.97215 | SlogP: 4.4592 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0869705 | Sterimol/B1: 2.42915 | Sterimol/B2: 2.80063 | Sterimol/B3: 6.22108 |
Sterimol/B4: 6.4116 | Sterimol/L: 18.533 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 606.796 | Positive charged surface: 311.041 | Negative charged surface: 295.755 | Volume: 332.75 |
Hydrophobic surface: 400.675 | Hydrophilic surface: 206.121 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |