Physical Properties | | | |
Molecular Weight: 404.487 g/mol | logS: -4.36578 | SlogP: 2.50972 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0956084 | Sterimol/B1: 3.19747 | Sterimol/B2: 3.94224 | Sterimol/B3: 4.72614 |
Sterimol/B4: 10.192 | Sterimol/L: 16.5738 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.381 | Positive charged surface: 436.205 | Negative charged surface: 226.176 | Volume: 377.25 |
Hydrophobic surface: 506.096 | Hydrophilic surface: 156.285 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |