Physical Properties | | | |
Molecular Weight: 412.466 g/mol | logS: -5.50654 | SlogP: 2.8296 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0511291 | Sterimol/B1: 3.32154 | Sterimol/B2: 4.90259 | Sterimol/B3: 5.51259 |
Sterimol/B4: 7.2334 | Sterimol/L: 18.5957 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 698.483 | Positive charged surface: 405.279 | Negative charged surface: 293.204 | Volume: 373.375 |
Hydrophobic surface: 528.477 | Hydrophilic surface: 170.006 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |