Physical Properties | | | |
Molecular Weight: 421.517 g/mol | logS: -4.87376 | SlogP: 1.26554 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0843576 | Sterimol/B1: 2.13654 | Sterimol/B2: 3.795 | Sterimol/B3: 4.44922 |
Sterimol/B4: 9.56023 | Sterimol/L: 19.3772 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 724.875 | Positive charged surface: 474.811 | Negative charged surface: 250.064 | Volume: 419 |
Hydrophobic surface: 594.501 | Hydrophilic surface: 130.374 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |