Physical Properties | | | |
Molecular Weight: 401.443 g/mol | logS: -4.77306 | SlogP: 1.89532 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0592779 | Sterimol/B1: 2.20191 | Sterimol/B2: 3.62583 | Sterimol/B3: 3.63041 |
Sterimol/B4: 10.3465 | Sterimol/L: 15.0065 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 601.862 | Positive charged surface: 288.175 | Negative charged surface: 291.535 | Volume: 351.375 |
Hydrophobic surface: 374.255 | Hydrophilic surface: 227.607 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |