Physical Properties | | | |
Molecular Weight: 390.532 g/mol | logS: -6.39137 | SlogP: 3.672 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0215111 | Sterimol/B1: 2.28664 | Sterimol/B2: 2.8066 | Sterimol/B3: 5.1297 |
Sterimol/B4: 6.47352 | Sterimol/L: 20.865 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 652.596 | Positive charged surface: 364.724 | Negative charged surface: 287.871 | Volume: 357.625 |
Hydrophobic surface: 469.577 | Hydrophilic surface: 183.019 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |