Physical Properties | | | |
Molecular Weight: 398.503 g/mol | logS: -4.89128 | SlogP: 3.6186 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.064402 | Sterimol/B1: 2.82644 | Sterimol/B2: 4.4727 | Sterimol/B3: 5.67479 |
Sterimol/B4: 6.51469 | Sterimol/L: 17.7393 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.64 | Positive charged surface: 509.064 | Negative charged surface: 153.576 | Volume: 391.625 |
Hydrophobic surface: 573.315 | Hydrophilic surface: 89.325 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |