Physical Properties | | | |
Molecular Weight: 371.403 g/mol | logS: -3.548 | SlogP: 3.8863 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.187691 | Sterimol/B1: 2.50714 | Sterimol/B2: 3.49126 | Sterimol/B3: 5.82153 |
Sterimol/B4: 8.28088 | Sterimol/L: 14.567 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 557.908 | Positive charged surface: 361.604 | Negative charged surface: 196.305 | Volume: 329.875 |
Hydrophobic surface: 386.507 | Hydrophilic surface: 171.401 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |