Physical Properties | | | |
Molecular Weight: 383.472 g/mol | logS: -5.82752 | SlogP: 3.61332 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0589244 | Sterimol/B1: 3.63688 | Sterimol/B2: 4.63386 | Sterimol/B3: 4.83925 |
Sterimol/B4: 6.12714 | Sterimol/L: 17.5664 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 636.616 | Positive charged surface: 360.194 | Negative charged surface: 276.422 | Volume: 351.875 |
Hydrophobic surface: 533.419 | Hydrophilic surface: 103.197 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |