Physical Properties | | | |
Molecular Weight: 382.484 g/mol | logS: -4.29902 | SlogP: 4.3333 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.125048 | Sterimol/B1: 2.54768 | Sterimol/B2: 2.74471 | Sterimol/B3: 6.28016 |
Sterimol/B4: 8.94421 | Sterimol/L: 18.1579 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 648.255 | Positive charged surface: 448.117 | Negative charged surface: 200.138 | Volume: 361.25 |
Hydrophobic surface: 582.586 | Hydrophilic surface: 65.669 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |